Archie Cochrane's challenge: can periodically updated reviews of all randomised controlled trials relevant to neurology and neurosurgery be produced?

Neurology, neurosurgery, controlled trials and academic accountability.

Can “realist” randomised controlled trials be genuinely realist?

In this paper, we respond to a paper by Jamal and colleagues published in Trials in October 2015 and take an opportunity to continue the much-needed debate about what applied scientific realism is. The paper by Jamal et al. is useful because it exposes the challenges of combining a realist evaluation approach (as developed by Pawson and Tilley) with the randomised controlled trial (RCT) design....

Grand Challenge Veterinary Neurology and Neurosurgery: Veterinary Neurology and Neurosurgery – Research for Animals and Translational Aspects

Neurology and neurosurgery are a recognized specialty in human and veterinary medicine (1) having many overlaps with other disciplines, such as internal medicine, surgery, imaging, and pathology. In some countries, in humanmedicine, neurology and neurosurgery are even recognized, separate subspecialties with different training pathways. In veterinary medicine, discussions are still ongoing abou...

Evidence-based medicine is not all randomised controlled trials and systematic reviews.

Is there evidence to support the popular belief that pregnancy results from sexual intercourse? Puliyel and colleagues 1 set out to test this hypothesis by conducting a Medline search of the literature from 1966 to 2004 using 'sexual intercourse' and 'preg-nancy' as keywords, and found 'no relevant or irrelevant paper' and certainly no systematic reviews or randomised controlled trials (RCTs) o...

Introducing “Agreement on what to Measure in Randomised Controlled Trials in Burn Care” Research Project

پروژه پژوهشی "توافق درباره‌ی پیامدهای قابل اندازه‌گیری در کارآزمایی های کنترل‌دار مربوط به مراقبت‌های سوختگی" توسط گروهی از پژوهش‌گران با تجربه، در حوزه سوختگی، زیر نظر دکتر Young از کشور انگلستان در حال انجام می‌باشد. هدف نهایی از انجام این مطالعه، تهیه و تدوین مجموعه‌ای از پیامدهای اساسی (core outcome set (COS)) است که در گزارش کارآزمایی های شاهد‌دار تصادفی مربوط به مراقبت‌های سوختگی باید مور...